Evaluation of a Spline Reconstruction Technique for SPECT: Comparison with FBP and OSEM

An efficient, two-dimensional, analytic, Spline Reconstruction Technique (SRT) for SPECT has been presented earlier in the literature. The SRT is a reconstruction algorithm based on an analytic formula of the inverse Attenuated Radon Transform which results from the approximation of the sinogram in terms of cubic splines. The algorithm incorporates the attenuation map obtained by a CT scan, to provide attenuation corrected images. The aim of this study is to evaluate the performance of the SRT algorithm, using phantoms and real SPECT/CT data, by comparing it with two commonly used reconstruction algorithms: FBP and OSEM.