Regioselective halogenation of aminopyrimidinyl-pyrrole carboxylic acid derivatives
2009
The regioselective synthesis of halogenated aminopyrimidinyl-pyrroles as useful scaffolds for the preparation of diversified selective kinase inhibitors is described. The chemistry is simple and mostly based on the use of N-halosuccinimides under mild reaction conditions but the regioselectivity observed is partially unexpected.
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