Tissue Histopathologic Injury in Renovascular Occlusive Disease

Many histopathologic findings within post-stenotic kidneys are nonspecific and represent conditions associated with aging, atherosclerosis and pre-existing hypertension. Two major abnormalities reported in patients with renovascular disease (RVD) are arteriolar nephrosclerosis and atheroembolic renal lesions. Other chronic renal “ischemia” markers include tubular atrophy, interstitial fibrosis and arteriolar sclerosis, but are less specific.