Effects of oral administration of lactulose in healthy horses

Summary Lactulose (1-4-galactosidofructose) was administered to seven healthy, mature horses at a dosage of 333 mg/kg, by mouth, three times daily for 11 days. There was a significant (P 0.05). There were no substantial changes in the results of physical examinations during the periods before, during and after administration in six horses. One horse developed signs of laminitis on the sixth day of administration, was removed from the study and responded well to treatment for laminitis.