1188 Is there a role for postoperative radiotherapy in cervical carcinoma

Objective The value of postoperative radiotherapy after extended radicai hysterectomy is disputed, because postoperative radiotherapy is commonly given to high risk patients without randomisation. Materials and methods 114 patients with squamous cell carcinoma of the cervix were grouped according to fractionation and dose of radiotherapy in a retrospective study: Group (A) more than 45 Gy continuous course. Group (B) less than 45 or split course radiotherapy. Results For 57 patients of the group (A) the 5 year relapse-free-survival was 67% vs. 26% in group (B) ( P  = 0.0002). 51 cases were available for Cox-regression analysis: the quality of radiotherapy, the size of the tumor and lymph node involvement were significant. Conclusion Dose and fractionation are of significant impact for the value of postoperative radiotherapy.