Temporal and Spatial Distribution Trends of Human Brucellosis in Liaoning Province, China

Brucellosis is a natural epidemic zoonotic disease. Liaoning province, northeast of China, has been among the top ten provinces with highest brucellosis incidence. In this study, the spatial and temporal distribution of brucellosis in Liaoning province from 2006 through 2017 was analyzed using the Bayesian theory of space-time modeling. The study found that in Liaoning province: (1) All regions of the entire study area were stable counties; (2) the risk of brucellosis declined slowly with time without an obvious trend; (3) the declining trend of disease risk in three sub-hot-spot counties was faster than the overall trend, whereas in other counties the trend was similar to the overall trend. Furthermore, the time and spatial trends of brucellosis incidence in Liaoning province were calculated and analyzed. These results may provide a theoretical and scientific basis for the public health department to develop targeted effective prevention and control measures for the disease.