Sublethal Endotoxemia Promotes Pulmonary Neutrophil Recruitment and TNF|[alpha]| Expression But Not Overt Lung Injury in Neonatal Rats 1484

Sepsis associated with respiratory failure is a major cause of morbidity and mortality in the newborn. In adult animal models, TNFα is a proinflammatory cytokine that has been associated with endotoxin-induced lung injury. We examined this association in a neonatal model of sepsis.