Multiple linear regression analysis of X-ray measurement and WOMAC scores of knee osteoarthritis

Objective:To perform Multiple Linear Regression analysis of X-ray measurement and WOMAC scores of knee osteoarthritis,and to analyze their relationship with clinical and biomechanical concepts.Methods:From March 2011 to July 2011,140 patients(250 knees) were reviewed,including 132 knees in the left and 118 knees in the right;ranging in age from 40 to 71 years,with an average of 54.68 years.The MB-RULER measurement software was applied to measure femoral angle,tibial angle,femorotibial angle,joint gap angle from antero-posterir and lateral position of X-rays.The WOMAC scores were also collected.Then multiple regression equations was applied for the linear regression analysis of correlation between the X-ray measurement and WOMAC scores.Results:There was statistical significance in the regression equation of AP X-rays value and WOMAC scores(P0.05),while there was no statistical significance in the regression equation of lateral X-ray value and WOMAC scores(P0.05).Conclusion:① X-ray measurement of knee joint can reflect the WOMAC scores to a certain extent.② It is necessary to measure the X-ray mechanical axis of knee,which is important for diagnosis and treatment of osteoarthritis.③ The correlation between tibial angle,joint gap angle on antero-posterior X-ray and WOMAC scores is significant,which can be used to assess the functional recovery of patients before and after treatment.