Screening mammography-detected ductal carcinoma in situ: mammographic features based on breast cancer subtypes

Abstract We evaluated the mammographic and histopathologic features of screening mammography-detected ductal carcinoma in situ (DCIS) based on the breast cancer subtypes determined by immunohistochemistry. A total of 94 patients with 94 screening mammography-detected DCIS were included in this study. Mammographically, human epidermal growth factor receptor 2 (HER2)-positive DCIS was more commonly associated with calcifications than estrogen receptor (ER)-positive and triple-negative DCIS ( P = .003). Histopathologically, HER2-positive DCIS and triple-negative DCIS were associated with high nuclear grade ( P ≤ .001) and comedo necrosis ( P ≤ .001) than ER-positive DCIS.