Spatial proximity of CD8 T cells to tumor cells as an independent biomarker for response to anti-PD-1 therapy.

Maarten Slagter,Elisa A. Rozeman,Huiwen Ding,Judith M. Versluis,Mesele Valenti,Dennis Peters,Annegien Broeks,Charlotte van Rooijen,Hugo M. Horlings,John B. A. G. Haanen,Erik Hooijberg,Lodewyk F. A. Wessels,Christian U. Blank,Ton N. M. Schumacher

Spatial proximity of CD8 T cells to tumor cells as an independent biomarker for response to anti-PD-1 therapy.

2020

Maarten Slagter
Elisa A. Rozeman
Huiwen Ding
Judith M. Versluis
Mesele Valenti
Dennis Peters
Annegien Broeks
Charlotte van Rooijen
Hugo M. Horlings
John B. A. G. Haanen
Erik Hooijberg
Lodewyk F. A. Wessels
Christian U. Blank
Ton N. M. Schumacher

10038Background: Only a subset of advanced melanoma patients respond to anti-PD-1 (aPD1) monotherapy. Upfront identification of (non-)responsiveness would help guide first-line treatment decisions,...

Keywords:

Cytotoxic T cell
Biomarker (medicine)
anti pd 1
Pathology
tumor cells
Medicine

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