Correlative Imaging in an Atypical Case of Mazabraud Syndrome

WEB This is a Web exclusive article. azabraud syndrome is a rare phenomenon that reflects the association between intramuscular myxoma and fibrous dysplasia, which is usually polyostotic. Approximately 40 cases have been described in the literature since the initial report by Henschen [1] in 1926. Mazabraud et al. [2] in 1967 emphasized the association as part of the spectrum of fibrous dysplasia. We present an atypical example of the syndrome and the characteristic difficulties encountered in interpretation of correlative images that necessitated biopsy of the bone and soft-tissue components for a firm diagnosis. Case Report A 53-year-old woman presented with a hard painless mass in the left deltoid muscle that had been noticed by her daughter. The patient had no symptoms, and the age of the mass was indeterminate. Sonography revealed a 51 × 46 × 48 mm oval hypoechoic soft-tissue mass within the deltoid muscle of the left arm. There was no involvement of the adjacent humerus. Radiographs of the humerus and forearm (Figs. 1A and 1B) showed multiloculated radiolucent expansile intramedullary masses involving the entire length of the left humeral shaft and most of the radius. There M