Factores pronósticos en cáncer de vesícula

Background. Gallbladder cancer is a rare and aggressive neoplasm. Objective. The purpose of this manuscript was to evaluate the prognostic factors associated with overall survival in gallbladder cancer patients. Methods. We performed a retrospective study of the patients with gallbladder cancer who received attention in a tertiary referral center in Mexico City during a 13 year period (1990-2002). We evaluated demographic, clinical, pathological and treatment variables. The main outcome variable was overall survival. The survival curves were constructed with the Kaplan and Meier method and compared with the log-rank test. Multivariate analyses was performed with the Cox regression method. We considered significant p 3.0 g/dL were associated with better prognosis. On multivariate analysis, only surgery (p = 0.0001) and serum albumin > 3 g/dL (p = 0.002) remained significantly associated with better outcome. Conclusions. Most cases of gallbladder cancer presented with advanced stage. Serum albumin is a prognostic factor for survival in this group of patients.