Involvement of Fatty Acid Amide Hydrolase and Fatty Acid Binding Protein 5 in the Uptake of Anandamide by Cell Lines with Different Levels of Fatty Acid Amide Hydrolase Expression: A Pharmacological Study

Emmelie Björklund,Anders Blomqvist,Joel Hedlin,Emma Persson,Christopher J. Fowler

Involvement of Fatty Acid Amide Hydrolase and Fatty Acid Binding Protein 5 in the Uptake of Anandamide by Cell Lines with Different Levels of Fatty Acid Amide Hydrolase Expression: A Pharmacological Study

2014

Emmelie Björklund
Anders Blomqvist
Joel Hedlin
Emma Persson
Christopher J. Fowler

Background:The endocannabinoid ligand anandamide (AEA) is removed from the extracellular space by a process ofcellular uptake followed by metabolism. In many cells, such as the RBL-2H3 cell line, i ...

Keywords:

Extracellular
Hydrolysis
Fatty acid-binding protein
Endocannabinoid system
Metabolism
Biology
Fatty acid amide hydrolase
Cell culture
Anandamide
Biochemistry

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