genetic markers for risk assessment for cardiovascular disease

2011 
Method for cardiovascular risk assessment in a subject, comprising the steps of determining in a sample isolated from said subject the presence of polymorphisms in the 27 positions within each of the nucleic acid sequences of SEQ ID NO: 1 to 12 wherein the presence in the 27 position C in SEQ ID NO: 1, C in SEQ ID NO: 2, T in SEQ ID NO: 3, C in SEQ ID NO: 4, C in SEQ ID NO: 5 C in SEQ ID NO: 6, T in SEQ ID NO: 7, G in SEQ ID NO: 8, A in SEQ ID NO: 9, A in SEQ ID NO: 10, A in SEQ ID NO: 1, and G in SEQ ID NO: 12, constituting the last four haplotype B ALOX5AP, is indicative of a risk of suffering a cardiovascular event, wherein the cardiovascular event is selected from the group of myocardial infarction, stroke atherothrombotic, angina pectoris, coronary revascularization due to coronary heart disease and peripheral arterial disease fatal or nonfatal.
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