Anticholinergic burden (prognostic factor) for prediction of dementia or cognitive decline in older adults with no known cognitive syndrome

This is a protocol for a Cochrane Review (Prognosis). The objectives are as follows: Primary objective: to assess whether ACB in older adults is a prognostic factor for future cognitive decline or dementia. Secondary objective(s): to assess whether ACB is a prognostic factor for older adults recruited in primary care, secondary care, or community settings (with setting used as the basis for subgroup analyses); whether ACB is associated with mortality; to compare the prognostic validity of respective ACB scales; and to examine the effect of duration of exposure and duration of follow‐up on the ACB‐dementia risk association.