A Facile One-Step Synthesis of Phosphatidylhomoserines by Phospholipase D-Catalyzed Transphosphatidylation.

Phospholipase D from Streptomyces effectively catalyzed the transfer reaction of the phosphatidyl residue from phosphatidylcholines to the primary hydroxyl group of homoserine in a two-phase system. Various phosphatidylhomoserines were easily prepared in good yields by this reaction.