Preparation and characterization of stable fluorescent As4S4/ZnS/Fe3O4 nanosuspension capped by Poloxamer 407 and folic acid

Novel drug delivery systems containing advanced materials are currently the focus of many scientists, particularly in the field of medicine. Nowadays, these materials can play an important role when the authors talk about human health and especially the need to develop personalized treatment. In this work, multiparticulate As4S4/ZnS/Fe3O4 nanocomposite based on components possessing promising therapeutic, photoluminescent, and magnetic functionality was prepared by the milling. Subsequently, it was covered with the bio-compatible polymer Poloxamer 407 and/or folic acid for the functionalization of inorganic material. The samples were studied from the structural (X-ray powder diffraction analysis), magnetic, and optical (UV–Vis and photoluminescence spectroscopies) point of view. Particle size distribution and zeta potential measurements were performed to determine long-term stability of these nanosuspensions. Fourier transform infrared spectroscopy was used to identify bonding between organic and inorganic entities. Prominent optical fluorescence properties were found in a sample containing folic acid.