The evaluation of insertion and deletion polymorphism in population and personal identification amidst Chinese populations

For comprehensive understanding of practical application and evaluation on the power of 30 commonly used InDels (Qiagen Investigator DIPplex ® kit), we captured population data from 25 Chinese populations and employed F-statistics for population genetics analysis. The results indicated that the distributions of allelic frequencies among populations were in different levels. Furthermore, the phylogeny conforming pairwise F ST distances showed that the differentiation of majority populations were consistent with their geographic locations and historic dispersals. We conduct the comprehensive correlation analysis between F ST and heterozygosity of 30 InDel loci and provided strong evidence for ongoing InDel loci selection. The F ST values of 30 InDels were calculated within 25 Chinese populations, and then, these loci were characterized definitely based on their roles in population genetics or individual identification. Data indicated that 17 InDels with F ST