Nestin derived synthetic peptides and their use

A synthetic peptide having the nestin expression inducibility to induce the expression of nestin in astrocytes, and nestin expression inducing agent comprising as an active ingredient the peptide derived astrocytes to one feature to supply the nestin expression inducer provides a method of producing nestin high expressing cells, a. Nestin expression inducer provided by the present invention, one in the amino acid sequence, or the amino acid sequence of SEQ ID NO: 1, 2, or 3 amino acid residues or any amino acid sequence that is formed by conservative substitutions synthetic peptides containing the nestin-inducing peptide sequence consisting of an active ingredient. Further, the method of producing nestin high expression cells derived from astrocytes that are provided by the present invention comprises providing a culture of astrocytes, and, at least for supplying one nestin expression inducer in the astrocyte cultures It encompasses.