Recent advances in liquid chromatography—mass spectrometry and capillary zone electrophoresis—mass spectrometry for protein analysis
1991
Abstract The utility of the combination of separations techniques, such as liquid chromatography and capillary zone electrophoresis, with mass spectrometry in applications involving protein analysis is discussed. The use of continuous-flow fast atom bombardment and electrospray ionization mass spectrometry is compared for the analysis of tryptic digests. For liquid chromatography, both microbore and slurry-packed capillary bore columns were used to separate peptides from proteolytic digests.
Keywords:
- Thermospray
- Electrospray ionization
- Liquid chromatography–mass spectrometry
- Capillary electrophoresis–mass spectrometry
- Sample preparation in mass spectrometry
- Analytical chemistry
- Protein mass spectrometry
- Direct electron ionization liquid chromatography–mass spectrometry interface
- Mass spectrometry
- Chromatography
- Chemistry
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