Paradoxical arteriole constriction compromises cytosolic and mitochondrial oxygen delivery in the isolated saline-perfused heart

Abigail V. Giles,Junhui Sun,Armel N. Femnou,Sarah Kuzmiak-Glancy,Joni Taylor,Raul Covian,Elizabeth Murphy,Robert S. Balaban

Paradoxical arteriole constriction compromises cytosolic and mitochondrial oxygen delivery in the isolated saline-perfused heart

2018

Abigail V. Giles
Junhui Sun
Armel N. Femnou
Sarah Kuzmiak-Glancy
Joni Taylor
Raul Covian
Elizabeth Murphy
Robert S. Balaban

Regional tissue anoxia is a common finding in the ubiquitous saline-perfused heart but is not found in vivo. Noninvasive optical techniques confirmed the presence of regional anoxia under control c...

Keywords:

Biochemistry
Oxygen
Saline
In vivo
Arteriole
Cytochrome c oxidase
Pharmacology
Cytosol
Biology
Myoglobin
Constriction
Diabetes mellitus

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