Synthesis and transformations of derivatives and analogs of α-cyanocinnamic acid

A reaction of ethyl α-cyanoacetate with 5-arylfurfurals, furfural, and 4-methoxybenzaldehyde in alkaline water medium gives rise to 3-substituted 2-cyanoacrylic acids in high yield. The reaction of the corresponding acyl chlorides with diethylamine and aniline or with β-hydroxyethyl methacrylate and hexadecanol afforded the appropriate amides and esters.