B-Typ-natriuretisches Peptid
2003
Abstract
B-natriuretic peptide (BNP) is a 32-amino acid polypeptide secreted
from the cardiac ventricles in response to ventricular
volume expansion and pressure overload. BNP levels are elevated
in patients with symptomatic left ventricular dysfunction,
and levels correlate with severity of symptoms and with
prognosis. Numerous studies indicate that BNP may considerably
improve the management of patients with heart failure
and may become a routine serum parameter in clinical medicine.
In this review, the utility of BNP in different clinical settings
will be discussed.
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