The role of autophagy in the pathogenesis of bronchial asthma

Autophagy is a defense and stress regulatory mechanism.Cells can adjust its biological activity and function trough autophagy.Recently people found that autophagy has an important role in the development of metabolic disease,neurological degenerative diseases,infections,immunity and tumor and so on.Bronchial asthma(asthma)is a kind of familial and polygenic hereditary disease,affected by genetic and environmental factors.Autophagy play an important role in the pathogenesis of asthma mainly in terms of innate and acquired immunity,pathogen infection,genetic. Key words: Autophagy; Asthma; Immunity; Pathogens; Autophagy related genes