Analysis on related factors of systemic inflammatory response syndrome after percutaneous nephrolithotomy in the treatment of upper urinary tract stones

Objective To investigate the related factors of systemic inflammatory response syndrome after percutaneous nephrolithotomy in the treatment of upper urinary tract stones. Methods The clinical data of 101 patients after percutaneous nephrolithotomy from August 2016 to April 2018 in Miyun Teaching Hospital, Capital Medical University were retrospectively analysed. Screened the independent variable such as gender, with fever or not, with diabetes or not, with hydronephrosis or not, urine leucocyte count, volume of urinary calculi, CT attenuation value of urinary calculi and presence of intraoperative infection, and analyzed the relationship those with systemic inflammatory response syndrome after surgery. Univariate and multivariate logistic regression analysis the factors related to systemic inflammatory response in patients after surgery. Results Of the 101 patients, 62 cases was male, and 39 cases was female, 12 (11.9%) suffered postoperative systemic inflammatory response syndrome. Univariate regression analysis indicated that the risk factors of systemic inflammatory response syndrome after percutaneous nephrolithotomy were gender, with diabetes or not, urine leucocyte count, volume of urinary calculi and presence of intraoperative infection. Furthermore, multivariate logistic regression analysis revealed that with diabetes, intraoperative infection, urine leucocyte count and volume of urinary calculi were the independent factors of systemic inflammatory response syndrome after percutaneous nephrolithotomy. Conclusion Patients with diabetes, intraoperative infection, urine leucocyte count and volume of urinary calculi could be predicted as the independent factors of systemic inflammatory response syndrome after percutaneous nephrolithotomy, but it has no relationship with gender, with a history of fever or not, with hydronephrosis or not, and CT attenuation value of urinary calculi. Key words: Nephrostomy, percutaneous; Urinary calculi; Systemic inflammatory response syndrome