Effect of auricular-plaster therapy indiabetes patients with insomnia: a systematic review

Objective To evaluate the efficacy of auricular-plaster therapy indiabetes patients with insomnia, and provide suggestions for treatment. Methods The relevant randomized controlled trials and quasi-randomized controlled trials about using auricular-plaster therapy in diabetes patients with insomnia were searched in Cochrane Library, JBI, EMbase, Chinese Biological Medical Database (CBM), Wanfang Data, VIP, China National Knowledge Internet(CNKI) and Pub Med. Information was selected. Retrieval time was limited from the foundation of those database to January 1st 2016. We use the Review manager 5.3 analysis software to conduct Meta-analysis. Results 10 primary studies were included, which involved in 1 315 patients. Meta-analysis was processed based on different intervention methods and various outcome indicators. ①Different intervention methods: the effective rate of the auricular-plaster therapy group were higher than the control group, with significant differences [OR=7.56, 95%CI(3.92, 14.58), P<0.000 01]; The effective rate of the comprehensive group (including auricular-plaster therapy) were higher than the control group, with significant differences [OR=3.45, 95%CI(2.60, 4.57), P=0.009]; ②Different results of outcome indicators, comprehensive interventionhas significant improvementonthe sleep quality of patients [MD=-1.96, 95%CI(-2.33, -1.59), P<0.000 01]; Moreover, comprehensive intervention could control postprandial blood glucose within twohours, with significant differences [MD=-1.86, 95%CI(-1.94, -1.78), P<0.000 01]. Conclusions Theauricular-plaster therapy can improve the sleep quality and sleep effect of diabetes patients with insomnia. However, because of the large literature difference, the results of the meta-analysis should be critical treated. Key words: Diabetes; Sleep initiation and maintenance disorders; Meta-analysis; Auricular-plaster therapy