Heparoprotective activity-A Review

Liver diseases are a major problem of worldwide proportions and liver damage is very common since liver has the capacity to detoxicate toxic substances. In this review some of the plants with their extract studied for protective effect in liver diseases were summerised. The varios isolated compounds studied herein are Andrographolide, neo-andrographolide, bacoside-A, colchicine, populnin, naringenin, echinacoside, kolaviron, ternatin, indigtona, rubiadin, bacicalein, baicalin, wogonin, punicalagin, punicalin for their hepatoprotective activity. There are several chemicals have been known to induce heptotoxicity by producing reactive species which cause depletion in tissue thiol, lipid peroxidation, plasma membrane damage like carbontetrachloride, paracetomol, thioacetamide, antituberculer drugs, D galactosamine, liposachharide and arsenic etc.