Synergistic anti-tumor activity and mechanisms of total glycosides from Cimicifuga dahurica in combination with cisplatin.

Leilei Zhang,Jianyong Si,Lijing Zhang,Huo Xiao-wei,Li Lin,Ruyi Li,Dan Chen,Li Cao

Synergistic anti-tumor activity and mechanisms of total glycosides from Cimicifuga dahurica in combination with cisplatin.

2016

Leilei Zhang
Jianyong Si
Lijing Zhang
Huo Xiao-wei
Li Lin
Ruyi Li
Dan Chen
Li Cao

Objective To determine the effect and mechanism of combination treatment of the total glycosides from Cimicifuga dahurica (TGCD) and cisplatin (CDDP) in vitro in human colon cancer cells (HCT-8) and in vivo in mouse hepatoma cells (H22)-bearing mice.

Keywords:

Diabetes mellitus
In vivo
Colorectal cancer
Cimicifuga dahurica
Cisplatin
Glycoside
Pharmacology
Medicine
In vitro
combined treatment
antitumor activity

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