Influence of Plasma Protein on Bacterial Adhesion to Biomaterials

Implant-associated infection is a serious problem in the clinical application of biomaterials, which greatly restricts the generalization of cardiovascular biomaterials, while bacterial adhesion is the initial cause for implant-associated infections of cardiovascular biomaterials. Therefore, the prevention of bacterial adhesion to the biomaterials plays a crucial role in the cure of biomaterial center infection. It has reported that human plasma protein influences the bacterial adhesion to biomaterials. Some plasma proteins inhibit bacterial adhesion, whereas some promote it. Study on the correlation between plasma protein and bacterial adhesion to the biomaterials is of great importance in the prevention and cure of biomaterials center infection.