Molecular cloning of an import precursor of the δ-subunit of the human mitochondrial ATP synthase complex

Two types of cDNA clones encoding a precursor of the δ-subunit of the human mitochondrial F 0 F 1 ATP synthase complex (EC 3.6.1.34) have been isolated from a human cDNA library. Both clones contain a 504 basepair open reading frame that encodes a polypeptide with a presequence 22 amino acids in length and a mature protein 146 residues in length. The difference between the two types of cDNA clones is the presence of a 296 basepair insert in the 3′ untranslated region of the δ-subunit cDNA in one of the types.