An Experimental Study on Changes of Lysozyme Content in Rat Model with Lung "Qi" Deficiency Syndrome

Objective To determine lysozyme content in tracheal washes,pulmonary tissue and serum of rat model with lung "Qi" Deficiency syndrome,so to provide a basis for objective and quantitative diagnosis and further studies of the syndrome.Methods The rat model of Lung Qi Deficiency Syndrome was induced by smoking and Pseudomonas aeruginosa infection and the content of lysozyme in tracheal washes,pulmonary tissue and serum in all groups were examined.Results Compared with control group,the content of lysozyme in racheal washes,pulmonary tissue was decreased significantly.Conclusion The change of lysozyme content in racheal washes,pulmonary tissue in the rat model can be used as an important and objective indicator of lung "Qi" deficiency syndrome.