Aldosterone Production in Human Adrenocortical Cells Is Stimulated by High-Density Lipoprotein 2 (HDL2) through Increased Expression of Aldosterone Synthase (CYP11B2)

Yewei Xing,Anthony Cohen,George H. Rothblat,Sandhya Sankaranarayanan,Ginny Weibel,Lori Royer,Omar L. Francone,William E. Rainey

Aldosterone Production in Human Adrenocortical Cells Is Stimulated by High-Density Lipoprotein 2 (HDL2) through Increased Expression of Aldosterone Synthase (CYP11B2)

2011

Yewei Xing
Anthony Cohen
George H. Rothblat
Sandhya Sankaranarayanan
Ginny Weibel
Lori Royer
Omar L. Francone
William E. Rainey

HDL2 stimulates aldosterone production through the activation of calcium signaling and aldosterone synthase (CYP11B2) expression in human H295R adrenocortical cells.

Keywords:

Aldosterone
Adrenal cortex
Steroid hormone
Diabetes mellitus
High Density Lipoprotein-2
Mineralocorticoid
Internal medicine
Endocrinology
Aldosterone synthase
Biology
Calcium signaling

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