Identification of a novel mechanism of action of fingolimod (FTY720) on human effector T cell function through TCF-1 upregulation
2015
Background
Fingolimod (FTY720), the first oral treatment for multiple sclerosis (MS), blocks immune cell trafficking and prevents disease relapses by downregulation of sphingosine-1-phosphate receptor. We determined the effect of FTY720 on human T cell activation and effector function.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
69
References
20
Citations
NaN
KQI