Purpurone, an inhibitor of ATP-citrate lyase: a novel alkaloid from the marine sponge Iotrochota sp

A novel compound, purpurone (1), with ATP-citrate lyase inhibitory activity, was isolated from the marine sponge Iotrochota sp. Its structure was established mainly on the basis of NMR spectroscopic data. Purpurone represents the first example of a new class of marine products