Simulation of X-ray phase contrast using GATE

We describe the first developments towards a Monte Carlo X-ray phase contrast imaging simulator for the medical imaging and radiotherapy simulation software GATE. Phase contrast imaging is an imaging modality taking advantage of the phase shift of X-rays. This modality produces images with a higher sensitivity than conventional, attenuation based imaging. As the first developments towards Monte Carlo phase contrast simulation, we implemented a Monte Carlo process for the refraction and total reflection of X-rays, as well as an analytical wave optics approach for generating Fresnel diffraction patterns. The implementation is validated against data acquired using a laboratory X-ray tomography system. The overall agreement between the simulations and the data is encouraging, which motivates further development of Monte Carlo based simulation of X-ray phase contrast imaging. These developments have been released in GATE version 8.2.