In vitro model to proof the efficacy of 2 foil drainage systems for abdominal negative pressure therapy

Abstract The negative pressure therapy (NPT) is used as a method of treatment of open abdomen based on high fluid retention in the abdominal cavity based on infection and/or abdominal hypertension. Thereby, different foil systems are used to remove the fluid of the abdomen. Two foils, system 1 (Suprasorb ® CNP) and system 2 (AB-Thera ® ), two of the commercial abdominal negative pressure systems, were compared in an in vitro model with their abdominal fluid permeability. We compared both foils with respect to their permeability under the same predefined conditions with the help of a self-developed system with a commercially available sub-pressure pump. System 2 original foil system did not show any measureable flow. System 1 showed a highly significant, higher permeability than the single layer of system 2. This supports the hypothesis that system 2 works in terms of an “overflow system”.