Cerclage family technologies for cathether based treatment of atriventricuar valve disease (MR, TR), and intraseptal energy delivery (physiologic pacing, intraseptal RF ablation)

Cerclage family technoologies consists of 4 technologies that are basically using proximal interventricular septal perforator vein so as to traverse or approach bsal interventricular septum from coronary sinus. Although each technology is independent each other, the procedures are largery same. First, mitral loop cerclage (MLC) is a transcathehter mitral indirect annuloplasty. Second, Cerclage T-Block (CTB) is a trancatheter treatment of tricuspid regurgitation. Especially, Cerclage T-Block can  also induce the same effect of MLC simultaneously  becasue CTB is built on top of MLC platform. This unique feature can expect the treatment of double regurgitation (MR and TR) by only one procedure with one device. Third, ‘cerclage pacing’ is delivering pacing stimuls nearby his conduction system  to have physiologic pacing, Fourth, intraseptal RF energy can be dilvered  to induce septal reduction for Hypertrophic obstructive cardiomyopathy patents with the same approach. Several human trials have been done or  impending.