Development and characterization of PLGA nanoparticles containing 1,3-dihydroxy-2-methylxanthone with improved antitumor activity on a human breast cancer cell line

Maribel Teixeira,Madalena Pedro,Maria São José Nascimento,Madalena Pinto,Carlos Maurício Barbosa

Development and characterization of PLGA nanoparticles containing 1,3-dihydroxy-2-methylxanthone with improved antitumor activity on a human breast cancer cell line

2019

Maribel Teixeira
Madalena Pedro
Maria São José Nascimento
Madalena Pinto
Carlos Maurício Barbosa

AbstractInterest on xanthones has been growing considerably due to their broad spectrum of biological activities. 1,3-Dihydroxy-2-methylxanthone (DHMXAN) showed a significant inhibitory effect on t...

Keywords:

PLGA
Biodegradable polymer
MCF-7
Nanoparticle
Nanocapsules
Nuclear chemistry
Cancer cell
Surface charge
Solvent
Chemistry
Chromatography
Organic chemistry
antitumor activity
cancer cell lines
human breast
plga nanoparticles
Biochemistry

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