Predictors of Durable Electrical Isolation in the Setting of Second Generation Cryoballoon Ablation: A Comparison between Left Superior, Left Inferior, Right Superior and Right Inferior Pulmonary Veins

AIM: The aim of this study is to assess specific per-vein procedural predictors of pulmonary vein (PV) late reconnection in cryoballoon ablation (CbA) METHODS AND RESULTS: We enrolled 148 consecutive patients undergoing a redo procedure after a previous index CbA in our center. A reconnection in at least one PV was found in 80 patients (54.1%) and the most frequently reconnected PV was the right inferior pulmonary vein (RIPV). Overall, pulmonary vein reconnection (PVr) was associated with longer time to -40 degrees C (Tt-40 degrees C) (54.4 +/- 21.7 vs 67.6 +/- 27.6 seconds; P < .001), warmer nadir temperature (NT) (-49.7 degrees C +/- 5.4 degrees C vs -46.5 degrees C +/- 5.8 degrees C; P < .001) and temperature at 60 seconds (-41.8 degrees C +/- 4.5 degrees C vs -39.8 degrees C +/- 4.2 degrees C; P < .001). The performance of these predictors differed between the veins. In particular, a comparable behavior was observed for left superior pulmonary vein (LSPV) and right superior pulmonary vein (RSPV), where NT