The clinical risk factors and coronary angiography and coronary interventional characteristics of middle-aged women with suspected coronary heart disease

Objective To analyze the clinical risk factors and characteristics of coronary angiography and coronary interventional of the middle-aged women patients with suspected coronary heart disease(CHD) in order to accessing the impact of gender and age on CHD. Methods This study enrolled patients with clinical suspected CHD and undergone coronary angiography from January 1998 to December 2006. A total of 5685 patients were included in this study. According to age and gender, the patients were divided into middle-aged (40-59 y) or old-aged (60-79 y) group and female or male group. The clinical and angiography details were recorded and retrospectively analyzed. Results ⑴ In middle-aged group, the morbidity of hyperlipidemia was significantly lower in women(75.68%) than in men (88.80%) (P0.01). The morbidity of hypertension was significantly higher in women (59.42%) than in men (50.66%)(P0.01). The morbidity of diabetes had no differences between female(30.47%) and male group(33.42%)(P=0.98). The morbidity of old myocardial infarction was 11.48% of women and 42.50% of man(P0.01). The rate of confirmed CHD by coronary angiography was 36.64% of women and 69.10% of men(P0.01).The seriousness of coronary artery sternosis were significantly less in female group than in male group(P0.01). Women with confirmed CHD were less likely to be intervented than their male counterparts. ⑵Compared middle-aged with old-aged female patients,the morbidity of phyperlipidemia,hypertension,diabetes, old myocardial infarction, the rate of confirmed CHD by coronary angiography, the rate of intervention were all significantly lower in middle-aged female than in old-aged female patients. Conclusion Significant age and gender bias has been identified in patients with clinical suspected CHD and undergone coronary angiography. The distribution of the clinical risk factors of CHD and the morbidity and seriousness of CHD is different in different age and gender group.