GASTRIC CANCER INFILTRATING TO OTHER ORGANS

We retrospectively reviewed 183 patients with gastric cancer showing macroscopic infiltration to other organs (S3) who were treated during the past one decade. Radical resection (curative or relative noncurative resection) could be performed in only 61 patients (33.3%). Late results were very poor in the other patients not treated by radical resection; the cumulative 5-year survival rate was 25.2% after radical resection, 2.7% after absolute noncurative resection, and 0% without resection. In the patients treated by radical operation, the histological finding was si or sei in 24 (45.3%) of 53 patients with S3 via the primary lesion. In the 24 patients, the 5-year cumulative survival rate was 35.7% when the degree of lymph node metastasis was n1 (+) or less (14 patients) but very low when it was n2 (+) or more (10 patients). Peritoneal recurrence was observed in 76.9%. On the other hand, of 8 patients with S3 via lymph node metastasis, 2 survived for 3 years or more, and liver recurrence was observed in 60%. These results suggest that radical resection should be performed to improve late results of gastric cancers infiltrating to other organs. In addition, preventive measures against peritoneal or liver recurrence are needed.