Assessment of Long-Term Cognitive Impairment After Off-Pump Coronary-Artery Bypass Grafting and Related Risk Factors

Abstract Objectives To assess cognitive impairment after off-pump coronary-artery bypass grafting, with a particular emphasis on long-term follow-up and related risk factors. Design Prospective study. Setting Virgen de la Victoria University Hospital, Malaga, Spain. Participants Participants were 36 patients undergoing off-pump coronary-artery bypass grafting. Measurements Changes in the neuropsychological test battery administered from before to after surgery (1, 6, and 12 months). Postoperative cognitive impairment was defined by a significant decrease. Results A significantly multidomain (attention-executive functions, P P P P P P P P P P P P Conclusion A multidomain long-term postoperative cognitive impairment and a partial neurocognitive recovering were detected after off-pump coronary-artery bypass grafting and were associated with several nonspecific surgery factors. These findings may be useful when counseling patients before surgery and suggest the importance of long-term neurocognitive evaluation.