Isolation of New Delhi Metallo-ßeta- Lactamase-1(NDM-1) Producing Klebsiella pneumoniae in a Neonate in Kwazulu-Natal, South Africa

Isolation of New Delhi Metallo-seta- lactamase-1(NDM-1) producing Klebsiella pneumoniae in a neonate in KwaZulu-Natal, South Africa. Carbapenems have been a last line of defence in the treatment of infections caused by antimicrobialresistant Enterobacteriaceae. The emergence of resistance in Enterobacteriaceae mediated via carbapenemases is a major concern as these isolates show resistance to antibiotics commonly used to treat Gram-negative infections. The first documented case of NDM-1-producing Enterobacteriaceae in a neonate within 24 hours of birth is reported here. This is a case report of a neonate with New Delhi Metallo-Beta-lactamse-1 producing Klebsiella pneumoniae in Kwazulu Natal South Africa. Emergence of this organism is worrisome in the neonatal unit, since treatment options are restricted. Active surveillance is required to prevent spread of this organism. Strict infection control and rationale use of antimicrobials is required, to prevent acquisition of these organisms.