Influence of perlite sand on the skin in experiment

: In the present work influence of perlite sand has been studied on a skin of Sprague-Dawley male rat (300-350 g). The biopsy of intact rat skin has been used as control. Contact of the perlite sand with animals' skin causes the reaction of an inflammation amplifying with increase of duration of the influence of substance. Therefore, despite an inert chemical compound, long contact with perlite sand in conditions of production can promote development of skin diseases. From the result of this investigation it is concluded that perlite sand causes irritating action on the skin and it is necessary to apply additional protective means to workers contacting to this substance.