A Case Report of Cautious Use of Levosimendan in Patients of Acute Heart Failure and Multi-organ Damage: Potentially Reasonable and Salvageable

Levosimendan, an amazing organ protector in acute heart failure, is currently not recommended in the events of moderate-to-severe renal impairment and shock. We report two critical cases that suffered from such poor clinical conditions associated with acute heart failure. Given that there was no better solution for enhancing heart function, we used levosimendan with great caution. We also introduced new-generation hemodynamic monitor, and the result suggested the benefit of levosimendan. We concluded that even in the event of multi-organ damage, early and cautious use of levosimendan may not only be safe, but also beneficial in salvaging end-organ functions. Using hemodynamic monitor carefully will warrant the best benefit and evade potential side effects.