Trombosis asociada a asparaginasa en niños con leucemia linfoblástica aguda.

Asparaginase is a key drug in the treatment of acute lymphoblastic leukemia. However, is associated with a decrease in the synthesis of proteins involved in the coagulation and fibrinolysis process, which leads to thrombotic complications. The occurrence of these events has been reported after the initiation of treatment, reflecting a possible interaction between disease and therapy.