A JAMA Theme Issue on Women's Health: Call for Papers

The Multiple Risk Factor Intervention Trial 1 examined mortality from coronary heart disease in 12 866 men . The Health Professionals Follow-up Study 2 looked at the association between coffee consumption and heart disease in 45 589 men . The Physician's Health Study 3 found that low-dose aspirin therapy reduced the risk of myocardial infarction in 22 071 men . What about women ? Is there a gender gap in medical research? Is there gender bias in medical knowledge? And are there gender differences in access to and use of medical care? 4 Some cautious answers to these questions are provided in this issue ofThe Journal. Manson et al 5 review the data from their observational study of 87 000 nurses and suggest that there may be some protective effect of aspirin in preventing cardiovascular disease in women. However, these authors, as well as Appel and Bush 6 in an accompanying editorial, emphasize