Dehydration of isoxazoline N-oxides under electrophilic conditions – An alternative approach toward 3-haloisoxazoles

Abstract A new method was developed for the synthesis of fully substituted 3-haloisoxazoles. This process includes the synthesis of isoxazoline N-oxides from α-halonitroalkenes and subsequent dehydration mediated by the silyl triflate/triethylamine system.