Off-label use of antibacterial agents in Traffic Hospital of Shandong Province in 2016: a cross sectional study

Objective To determine the off-label use of antibacterial agents, we investigated and analyzed the current status about off-label use of antibacterial agents. Methods The random sampling was conducted to select the outpatient prescription including antibacterial agents from January to April in 2016.According to drug instructions, the off-label drug use of prescription was analyzed. Results 1 264 prescriptions involving 58 kinds of drugs were analyzed.The main categories of off-label drug use were no pediatric and elderly information(23.42%), indication(4.15%), dosage(6.31%), dosage range(62.95%) and administration route(3.15%). Conclusion The off-label use of antibacterial agents is common in our hospital.It's in need to regulate off-label drug use. Key words: Prospectuses; Drug prescriptions; Anti-bacterial agents; Ambulatory care