АНТИГИПОКСИЧЕСКАЯ АКТИВНОСТЬ НОВОГО КОМПЛЕКСНОГО СОЕДИНЕНИЯ ОКСИМЕТИЛУРАЦИЛА С СУКЦИНАТОМ НАТРИЯ
2017
On the models of acute hemic and acute histotoxic hypoxia, the activity of a new complex compound of 5-hydroxy- 6-methyluracil with sodium succinate was studied. It was found out that the compound under investigation in respects to its activity is comparable or superior to reference preparations-reamberin, sodium succinate and oxymethyluracil, and has low toxicity at intragastric and intraperitoneal administration to mice. Based on the results of the studies, the patent of the Russian Federation was awarded.
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